doi: 10.1055/s-2007-1022247.
[-Cytokine level in malignant ascites and peripheral blood of patients with advanced ovarian carcinoma-]
[Article in
German]
Affiliations
- PMID: 8647364
- DOI: 10.1055/s-2007-1022247
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[-Cytokine level in malignant ascites and peripheral blood of patients with advanced ovarian carcinoma-]
[Article in
German]
Geburtshilfe Frauenheilkd.
1996 Feb.
Abstract
The concentrations of various cytokines were examined by ELISA in blood and in ascites from 14 patients with advanced ovarian cancer (stage IV). The control group consisted of 6 patients with benign gynaecological disorders. Compared with patients with benign gynaecological disorders, ascites and/or plasma of patients with ovarian cancer showed significantly higher levels of IL-6, IL-8, IL-10, TNF-alpha, and sIL-2R. There were no increases of IL-1 alpha, IL-1 beta, IL-2, IFN-gamma, and sCD14 levels. The possible pathogenetic significance of cytokines in ovarian cancer is discussed.
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