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. 1977 Jun;58(6):1795-806.
doi: 10.1093/jnci/58.6.1795.

Two syngeneic cell lines from human breast tissue: the aneuploid mammary epithelial (Hs578T) and the diploid myoepithelial (Hs578Bst) cell lines

A J Hackett, H S Smith, E L Springer, R B Owens, W A Nelson-Rees, J L Riggs, M B Gardner

Two syngeneic cell lines from human breast tissue: the aneuploid mammary epithelial (Hs578T) and the diploid myoepithelial (Hs578Bst) cell lines

A J Hackett et al. J Natl Cancer Inst. 1977 Jun.

Abstract

We characterized two human cell lines (Hs578T and Hs578Bst), which provide several unique features that should be useful in the study of breast disease. Hs578T, derived from a carcinosarcoma, is epithelial in origin. Hs578Bst, established from normal tissue peripheral to the tumor, is myoepithelial in origin. This is the first report of companion cell lines, one malignant and one normal, established from the same organ.

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