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. 1979 Feb 19;93(2):137-47.
doi: 10.1007/BF00406571.

Electron microscopical and biochemical investigations on retra viruses in spleen tissue in malignancy

S O Warnaar, J te Velde, G J den Ottolander, F Prins, H Mooren, G N van Muijen

Electron microscopical and biochemical investigations on retra viruses in spleen tissue in malignancy

S O Warnaar et al. J Cancer Res Clin Oncol. .

Abstract

Simultaneous biochemical and electron microscopical investigations on surgically removed spleens yielded evidence for the presence of reverse transcriptase containing (Retra) virus in two patients with hematological malignancies with spleen involvement. In three other patients with hematological diseases and in one control patient, the spleens were negative in both assays. The results of these combined studies support the view, that retraviruses are present in human malignancies.

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