Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Apr;43(1):139-45.
doi: 10.1016/0027-5107(77)90138-5.

Excision of gamma-ray induced thymine lesions by preparations from ataxia telangiectasia fibroblasts

J F Remsen, P A Cerutti

Excision of gamma-ray induced thymine lesions by preparations from ataxia telangiectasia fibroblasts

J F Remsen et al. Mutat Res. 1977 Apr.

Abstract

The capacity of whole cell sonicates of skin fibroblasts of normal individuals and patients with the autosomal recessive disease Ataxia telangiectasia (AT) to remove aerobic gamma-ray products of the 5,6-dihydroxydihydrothymine type (tgamma02) from exogenous DNA substrates was investigated. All four AT strains (AT CRL 1312, AT CRL 1343, AT GM 367, AT 4BI) possessed normal capabilities to excise tgamma02 from irradiated bacteriophage DNA and irradiated chromatin isolated from normal and AT-skin fibroblasts.

PubMed Disclaimer

Publication types