5' Terminal noncoding sequence heterogeneity in reovirus mRNA
- PMID: 866175
- PMCID: PMC342419
- DOI: 10.1093/nar/4.1.195
5' Terminal noncoding sequence heterogeneity in reovirus mRNA
Abstract
The nucleotide sequences of the mRNAs of reovirus appear to diverge near the 5' termini. Ribonuclease T1 digestion of methylated mRNA synthesized in vitro yielded seven different 5' terminal fragments of the form m7G5'pp5' GmpCpUp(Np)nGp. Chain length analysis showed that the parameter "n" in this structural formula assumes the values 3, 4 and 5.
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