Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Mar;4(3):503-11.
doi: 10.1093/nar/4.3.503.

Proflavine sensitivity of RNA processing in isolated nuclei

A Yannarell, M Niemann, D E Schumm, T E Webb
Free PMC article

Proflavine sensitivity of RNA processing in isolated nuclei

A Yannarell et al. Nucleic Acids Res. 1977 Mar.
Free PMC article

Abstract

The intercalating agent proflavine inhibits the processing and subsequent release of preformed messenger RNA and ribosomal RNA from isolated liver nuclei to surrogate cytoplasm. The direct effect of proflavine on these processes, as monitored in a reconstituted cell-free system, supports the theory that base-paired segments (i.e. hairpin loops) in the precursor RNA's are involved as recognition sites in nuclear RNA processing.

PubMed Disclaimer

References

    1. Annu Rev Biochem. 1974;43(0):621-42 - PubMed
    1. Science. 1971 Oct 29;174(4008):507-10 - PubMed
    1. Nat New Biol. 1973 Oct 17;245(146):201-3 - PubMed
    1. J Mol Biol. 1968 May 28;34(1):49-60 - PubMed
    1. J Mol Biol. 1971 Jun 14;58(2):555-65 - PubMed

Publication types