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. 1996 Jun;52(2):492-9.

Fitting a multiplicative incidence model to age- and time-specific prevalence data

I C Marschner  1
Affiliations
  • PMID: 8672700

Fitting a multiplicative incidence model to age- and time-specific prevalence data

I C Marschner. Biometrics. 1996 Jun.

Abstract

We discuss the assessment of age- and time-specific disease incidence using prevalence data. A method is described for conveniently fitting a discrete-time multiplicative model, subject to positivity constraints, using the EM-algorithm. Together with smoothing, it allows essentially nonparametric assessment of incidence trends. The method is illustrated using previously analyzed data on toxoplasmosis.

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