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. 1996 Jun 1;139(2-3):149-53.
doi: 10.1111/j.1574-6968.1996.tb08195.x.

The arsenical resistance operon of IncN plasmid R46

D F Bruhn  1 , J Li, S Silver, F Roberto, B P Rosen
Affiliations

The arsenical resistance operon of IncN plasmid R46

D F Bruhn et al. FEMS Microbiol Lett. .

Abstract

The arsenical resistance operon of the IncN plasmid R46 consists of 4696 bp and starts with predicted transcriptional control and initiation signals, followed by five genes, arsD, arsA, and arsC. The corresponding Escherichia coli chromosomal ars operon and two staphylococcal ars operons lack arsA and arsD genes. The R46 system contains only the second known versions of arsA and arsD, after those of plasmid R773. Western blot analysis identified the R46 proteins using antibodies against R773 ArsA, ArsD and ArsR.

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