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Review
. 1996 Jul;35(1):88-95.
doi: 10.1016/S0190-9622(96)90502-2.

Sign of Leser-Trélat

R A Schwartz  1
Affiliations
Review

Sign of Leser-Trélat

R A Schwartz. J Am Acad Dermatol. 1996 Jul.

Abstract

The sign of Leser-Trélat is rare. It is defined as the sudden eruption of multiple seborrheic keratoses caused by a malignancy. Because both seborrheic keratoses and cancer are common in the elderly, it is not always easy to tell from the literature or in any given patient if this sign is present. In fact, its validity has been questioned. Its association with malignant acanthosis nigricans is one of several of its features that support its legitimacy as a true paraneoplastic disorder.

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Comment in

  • Sign of Leser-Trélat.
    Farrell AM, Dawber RP. Farrell AM, et al. J Am Acad Dermatol. 1997 Jul;37(1):138-9. doi: 10.1016/s0190-9622(97)70232-9. J Am Acad Dermatol. 1997. PMID: 9216543 No abstract available.
  • Sign of Leser-Trélat and mycosis fungoides.
    McCrary ML, Davis LS. McCrary ML, et al. J Am Acad Dermatol. 1998 Apr;38(4):644. doi: 10.1016/s0190-9622(98)70143-4. J Am Acad Dermatol. 1998. PMID: 9555814 No abstract available.

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