[Lichen planus and vaccination against hepatitis B]
- PMID: 8687059
[Lichen planus and vaccination against hepatitis B]
Abstract
Introduction: The association of lichen planus with liver diseases is now well established. Lichen planus following hepatitis B vaccination are much more unusual. We report here the fifth case of this kind.
Case report: A 16 years old girl developed a purely cutaneous lichen planus one week after the first injection of hepatitis B vaccine Gen Hevac B (Institut Pasteur), which appeared again 3 days after the second injection. The histologic features shown lichenoid pattern with intense keratinocytes necrosis more in favor of lichenoid drug eruption than lichen planus.
Discussion: According to our knowledge, only four similar cases have been previously reported. Comparison between the different vaccines used shows that only the HBs antigen and its epitope S could be involved in the lichen planus eruption. Our case is specific due to the early appearance of the eruption after the first injection and by its histologic features.
Conclusion: New cases of lichen planus following hepatitis B vaccination should help to explain the causal relationship between lichen planus eruption and hepatitis B vaccination.
Similar articles
-
[Lichen planus in children: role of the campaign for hepatitis B vaccination].Ann Dermatol Venereol. 1998 Jul;125(6-7):399-403. Ann Dermatol Venereol. 1998. PMID: 9747294 French.
-
Two case reports of cutaneous adverse reactions following hepatitis B vaccine: lichen planus and granuloma annulare.J Eur Acad Dermatol Venereol. 2004 Sep;18(5):603-6. doi: 10.1111/j.1468-3083.2004.00989.x. J Eur Acad Dermatol Venereol. 2004. PMID: 15324406
-
Lichen planus occurring after hepatitis B vaccination: a new case.J Am Acad Dermatol. 2001 Oct;45(4):614-5. doi: 10.1067/mjd.2001.114590. J Am Acad Dermatol. 2001. PMID: 11568757
-
Lichenoid reaction to hepatitis B vaccination.Australas J Dermatol. 1997 Aug;38(3):152-4. doi: 10.1111/j.1440-0960.1997.tb01134.x. Australas J Dermatol. 1997. PMID: 9293664 Review.
-
Lichen planus induced by hepatitis B vaccination: a new case and review of the literature.Int J Dermatol. 2004 Aug;43(8):562-4. doi: 10.1111/j.1365-4632.2004.01740.x. Int J Dermatol. 2004. PMID: 15304176 Review.
Cited by
-
Hepatitis B vaccination and associated oral manifestations: a non-systematic review of literature and case reports.Ann Med Health Sci Res. 2014 Nov;4(6):829-36. doi: 10.4103/2141-9248.144870. Ann Med Health Sci Res. 2014. PMID: 25506472 Free PMC article. Review.
-
A comprehensive review of oral microenvironment changes and orofacial adverse reactions after COVID-19 vaccination: The good, the bad, and the ugly.Health Sci Rep. 2024 Mar 13;7(3):e1967. doi: 10.1002/hsr2.1967. eCollection 2024 Mar. Health Sci Rep. 2024. PMID: 38482134 Free PMC article.