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Case Reports
. 1996 Jan;98(1):5-8.
doi: 10.1016/0013-4694(95)00211-1.

Periodic lateralized epileptiform discharges in multiple sclerosis

D R Chabolla  1 , J L Moore, B F Westmoreland
Affiliations
Case Reports

Periodic lateralized epileptiform discharges in multiple sclerosis

D R Chabolla et al. Electroencephalogr Clin Neurophysiol. 1996 Jan.

Abstract

We report an unusual cause of periodic lateralized epileptiform discharges (PLEDs) in a young man with a long history of multiple sclerosis. Two exacerbations of multiple sclerosis, 3 years apart, were complicated by complex partial status epilepticus. After each episode, serial electroencephalograms revealed PLEDs (right frontal PLEDs in the first episode and right frontotemporal and bifrontal PLEDs in the second one), which resolved within 2 weeks. With the first episode, magnetic resonance imaging revealed an enhancing white matter lesion in the right frontal area, which improved after 3 weeks. We concluded that in each instance an exacerbation of multiple sclerosis caused the seizures.

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