doi: 10.1021/np50126a019.
Bruceanols G and H cytotoxic quassinoids from Brucea antidysenterica
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- PMID: 8691212
- DOI: 10.1021/np50126a019
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Bruceanols G and H cytotoxic quassinoids from Brucea antidysenterica
J Nat Prod.
1995 Dec.
Abstract
Two new quassinoids, bruceanols G [1] and H [4], were isolated from Brucea antidysenterica, and their structures were elucidated by spectral evidence and chemical transformation. Bruceanol G exhibited significant cytotoxicity against the COLO-205 and KB neoplastic cell lines with ED50 values of 0.44 and 0.55 microM, respectively.
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