[Toxic hepatitis caused by rifampin and isoniazid in treatment of tuberculosis (author's transl)]
[Article in
Spanish]
- PMID: 869341
Item in Clipboard
[Toxic hepatitis caused by rifampin and isoniazid in treatment of tuberculosis (author's transl)]
[Article in
Spanish]
An Esp Pediatr.
1977 Feb.
Abstract
Five children with tuberculosis were treated with isoniazid (20 mg./Kg./day) and rifampin (15 mg./Kg./day). After five to twenty seven days of treatment they presented anorexia, vomiting and jaundice. Hepatomegaly was found in two of them. High indirect bilirubin, S.G.O.T. and S.G.P.T. and low prothrombin levels were present in all of them. Eight to thirty one days after withdrawal of rifampin, all patients were well and their laboratory data was normal.
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