Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1995;3(3-4):309-17.

The hypothalamo-sympathetic nervous system modulates peripheral cellular immunity

T Hori  1 , T Katafuchi, S Take, Y Kaizuka, T Ichijo, N Shimizu
Affiliations
  • PMID: 8696299
Review

The hypothalamo-sympathetic nervous system modulates peripheral cellular immunity

T Hori et al. Neurobiology (Bp). 1995.

Abstract

Our findings reviewed in this article have revealed that the stimulation of opioid receptors of the hypothalamic neurons by interferon alpha and beta-endorphin synthesized in the brain or by stress causing the opioid-dependent analgesia suppresses the natural killer cytotoxicity, an important component of immunosurveillance, through an activation of the hypothalamic CRF-sympathetic nervous system.

PubMed Disclaimer

Publication types