Leukocyte adhesion deficiency: report of a case and review of the literature
- PMID: 8697667
Leukocyte adhesion deficiency: report of a case and review of the literature
Abstract
Leukocyte adhesion deficiency (LAD) is a rare inherited immunodeficiency that is characterized by deficiency of the beta 2 integrin leukocyte adhesion molecules Mac-1, LFA-1, and p150,95. We describe a case of the severe form of LAD in an infant with recurrent infections and with a complete deficiency of beta 2 integrin molecules, and review the clinical aspects of the syndrome.
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