Stereochemical considerations for constructing alpha-helical protein bundles with particular application to membrane proteins
- PMID: 869919
- PMCID: PMC1164662
- DOI: 10.1042/bj1630045
Stereochemical considerations for constructing alpha-helical protein bundles with particular application to membrane proteins
Abstract
The stereochemical constraints originally used to construct two- and three-stranded alpha-helical coiled-coils were generalized for aggregates of alpha-helices containing from 4 to 14 alpha-helices in tubular bundles. Certain features of bacteriorhodopsin show excellent correlations with these stereochemical constraints.
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