Comparative Study
doi: 10.1111/j.1365-2141.1977.tb00604.x.
The conformation of fibrinogen and fibrin: an electron microscopy study
- PMID: 870006
- DOI: 10.1111/j.1365-2141.1977.tb00604.x
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Comparative Study
The conformation of fibrinogen and fibrin: an electron microscopy study
Br J Haematol.
1977 Mar.
Abstract
A mica adsorption technique was used to prepare fibrinogen and early fibrin polymers for examination in the transmission electron microscope. Globular particles 10 +/- 3 nm in diameter were observed and a model for the process of aggregation of these globules into fibrous units is proposed. A comparison is made between the results obtained by the mica adsorption technique and those obtained by conventional preparation techniques involving fixation and staining.
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