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Review
. 1996:51:391-403; discussion 403-4.

The JAK-STAT pathway: summary of initial studies and recent advances

J E Darnell Jr  1
Affiliations
  • PMID: 8701087
Review

The JAK-STAT pathway: summary of initial studies and recent advances

J E Darnell Jr. Recent Prog Horm Res. 1996.

Abstract

Polypeptides redirect cells by causing immediate changes in gene transcription. A direct connection between polypeptide receptors on the cell surface and genes in the nucleus has been provided by the recognition of the JAK-STAT pathway. Results leading to our present understanding of this pathway are reviewed.

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