Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Mar;11(2):141-6.
doi: 10.1093/cvr/11.2.141.

Pathophysiological correlates of thallium-201 myocardial uptake in experimental infarction

V C DiCola, S E Downing, R K Donabedian, B L Zaret

Pathophysiological correlates of thallium-201 myocardial uptake in experimental infarction

V C DiCola et al. Cardiovasc Res. 1977 Mar.

Abstract

The pathophysiological correlates of thallium-201 (201TI) myocardial uptake were studied in a 24-hour-old closed-chest canine infarct model. Reduction in regional 201Tl uptake correlated well with the magnitude of tissue creatine phosphokinase depletion and microsphere estimates of transmural blood flow. In low flow endocardial regions 201Tl occasionally under-estimated the magnitude of flow reduction. Even slight reductions of 201Tl uptake (less than 0.86 of normal) were associated with histopathological and histochemical evidence of necrosis.

PubMed Disclaimer

Publication types

LinkOut - more resources