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Review
. 1996 Apr;10(2):293-320.
doi: 10.1016/s0889-8588(05)70340-3.

Therapy-related myeloid leukemia

Affiliations
Review

Therapy-related myeloid leukemia

M J Thirman et al. Hematol Oncol Clin North Am. 1996 Apr.

Abstract

One of the most serious possible consequences of cancer therapy is the development of a second cancer, especially leukemia. Several distinct subsets of therapy-related leukemia can be distinguished currently. These include classic therapy-related myeloid leukemia, leukemia that follows treatment with agents that inhibit topoisomerase II, acute lymphoblastic leukemia, and leukemias with 21q22 rearrangements or inv(16) or t(15;17). These types of leukemia are discussed in detail in this article.

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