A cause of misleading serum amylase concentrations in acute pancreatitis
- PMID: 870964
- DOI: 10.1177/003693307702200212
A cause of misleading serum amylase concentrations in acute pancreatitis
Abstract
The operative discovery of acute pancreatitis associated with gross hyperlipidaemia but a normal or high elevated serum amylase concentration has been described. We report a case of acute pancreatitis in which serial dilutions of serum resulted in a 338% rise in the serum amylase concentrations. The importance of appreciating this effect of hyperlipidaemia on the serum level measurements in patients with acute pancreatitis is re-emphasised.
Similar articles
-
Inhibition of serum and urine amylase activity in pancreatitis with hyperlipemia.Ann Surg. 1975 Jul;182(1):72-5. doi: 10.1097/00000658-197507000-00014. Ann Surg. 1975. PMID: 1147712 Free PMC article.
-
Elevated serum amylase in patients with chronic pancreatitis: acute attack or macroamylasemia?Pancreatology. 2014 Mar-Apr;14(2):114-6. doi: 10.1016/j.pan.2013.12.004. Epub 2014 Jan 8. Pancreatology. 2014. PMID: 24650965
-
[Amylase test in the diagnosis of acute pancreatitis].Rev Gastroenterol Mex. 1979 Apr-Jun;44(2):57-62. Rev Gastroenterol Mex. 1979. PMID: 462067 Spanish.
-
Possible mechanisms of normal amylase activity in hyperlipemic pancreatitis.Can Med Assoc J. 1976 Nov 20;115(10):1016-9. Can Med Assoc J. 1976. PMID: 206333 Free PMC article.
-
Amylase testing for abdominal pain and suspected acute pancreatitis.J Hosp Med. 2016 May;11(5):366-8. doi: 10.1002/jhm.2544. J Hosp Med. 2016. PMID: 27160507 Review. No abstract available.
Cited by
-
Serum amylase and lipase and urinary trypsinogen and amylase for diagnosis of acute pancreatitis.Cochrane Database Syst Rev. 2017 Apr 21;4(4):CD012010. doi: 10.1002/14651858.CD012010.pub2. Cochrane Database Syst Rev. 2017. PMID: 28431198 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources