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Review
. 1996 Jun;48(6):227-31.
doi: 10.1016/0300-2977(95)00075-5.

Vertebral bone destruction in sickle cell disease: infection, infarction or both

A Kooy  1 , L J de Heide, A J ten Tije, A H Mulder, H L Tanghe, J A Kluytmans, J J Michiels
Affiliations
Free article
Review

Vertebral bone destruction in sickle cell disease: infection, infarction or both

A Kooy et al. Neth J Med. 1996 Jun.
Free article

Abstract

Infectious and vaso-occlusive vertebral bone and joint destruction in two patients with sickle cell disease (SCD) are featured by H-shaped vertebrae, kyphotic angulation, osteolysis of endplates and collapse of intervertebral discs as shown by X-ray films and magnetic resonance imaging. Staphylococcal serology supported the diagnosis of staphylococcal osteomyelitis/spondylo-discitis in both SCD patients. The difficulties of establishing the causes and treatment of the osteoarthropathy in these particular cases are discussed in the light of the literature.

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