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. 1996 Jul 15;317 ( Pt 2)(Pt 2):343-6.
doi: 10.1042/bj3170343.

Phosphatidylserine-mediated adhesion of T-cells to endothelial cells

J Qu  1 , L A Conroy, J H Walker, F B Wooding, J A Lucy
Affiliations

Phosphatidylserine-mediated adhesion of T-cells to endothelial cells

J Qu et al. Biochem J. .

Abstract

Phosphatidylserine was exposed on the surface of human umbilical endothelial cells (ECV304) a few minutes after adding thrombin in vitro, as monitored by prothrombinase assays with and without annexin V. Jurkat T cells adhered to the thrombin-treated cells. The adhesion was inhibited by annexin V, indicating that it was mediated by exposed phosphatidylserine on the endothelial cells.

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