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. 1995;46(4):211-7.

HIV lymphadenopathy--a histopathological and immunomorphological study of 65 cases

B Walewska-Zielecka  1 , A Nowosławski
Affiliations
  • PMID: 8713287

HIV lymphadenopathy--a histopathological and immunomorphological study of 65 cases

B Walewska-Zielecka et al. Pol J Pathol. 1995.

Abstract

Lymph nodes from 65 HIV-infected persons were studied by morphological and immunomorphological methods. Early stages of HIV lymphadenopathy (follicular hyperplasia without fragmentation or follicular hyperplasia with severe fragmentation) were revealed in 92% of patients with PGL and the most advanced stadium of HIV-related lymphadenopathy (diffuse pattern) in 92% of AIDS patients. Striking B-cell activation and polyclonal proliferation, found in 19 lymph nodes (35% of advanced lymphadenopathy cases--follicular atrophy or diffuse pattern) justified separation of these cases as a particular subgroup of HIV lymphadenopathy.

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