Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1996 Apr;35(2):63-7.

[Pain therapy with rhenium-186 HEDP in multiple bone metastases]

[Article in German]
H Palmedo  1 , H Bender, A Schomburg, F Grünwald, G Schöneich, P Zamorra, K Reichmann, C Dierke-Dzierzon, P Mallmann, H J Biersack
Affiliations
  • PMID: 8721578
Clinical Trial

[Pain therapy with rhenium-186 HEDP in multiple bone metastases]

[Article in German]
H Palmedo et al. Nuklearmedizin. 1996 Apr.

Abstract

Aim: Therapeutic means for patients with painful bony metastases are strongly limited. In these patients, a systemic therapy with isotopes can be helpful. The aim of this study was to evaluate the efficacy of rhenium-186 HEDP for pain palliation in patients with disseminated bone metastases.

Methods: 30 patients taking analgesics because of bone pain received one or more injection of 1295 MBq 186Re HEDP for pain palliation.

Results: In 70% of the patients, therapy resulted in a significant reduction of pain. The average duration of pain relief was 4 weeks (1 week-2.5 months). The main side effects of therapy were a decrease of platelets (aver. 30000/microliters) and an increase of pain for 1-2 days (flare-phenomenon).

Conclusion: Therapy with rhenium-186 HEDP can be used complementarily to analgesic therapy in patients with painful, disseminated bone metastases.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources