Review
doi: 10.1016/s0952-7915(96)80059-8.
The molecular basis of somatic hypermutation of immunoglobulin genes
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- PMID: 8725944
- DOI: 10.1016/s0952-7915(96)80059-8
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Review
The molecular basis of somatic hypermutation of immunoglobulin genes
Curr Opin Immunol.
1996 Apr.
Abstract
Somatic hypermutation amplifies the variable region repertoire of immunoglobulin genes. Recent experimental evidence has thrown light on various molecular models of somatic hypermutation. A link between somatic hypermutation and transcription coupled DNA repair is shaping up.
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