Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1996 Jun;40(6):1552-4.
doi: 10.1128/AAC.40.6.1552.

Eucaryotic cells protect Borrelia burgdorferi from the action of penicillin and ceftriaxone but not from the action of doxycycline and erythromycin

P Brouqui  1 , S Badiaga, D Raoult
Affiliations
Comparative Study

Eucaryotic cells protect Borrelia burgdorferi from the action of penicillin and ceftriaxone but not from the action of doxycycline and erythromycin

P Brouqui et al. Antimicrob Agents Chemother. 1996 Jun.

Abstract

Despite appropriate antibiotic treatment, Lyme disease patients may have relapses or may develop chronic manifestations. The intracellular location of Borrelia burgdorferi suggests that antibiotics that penetrate cells will have greater efficiency. Doxycycline or erythromycin was more effective than penicillin or ceftriaxone in killing B. burgdorferi when the organism was grown in the presence of eucaryotic cells.

PubMed Disclaimer

References

    1. Lancet. 1988 May 28;1(8596):1191-4 - PubMed
    1. J Infect Dis. 1988 Oct;158(4):905-6 - PubMed
    1. Infect Immun. 1989 Apr;57(4):1324-6 - PubMed
    1. Am J Trop Med Hyg. 1995 Feb;52(2):128-33 - PubMed
    1. Infect Immun. 1991 Feb;59(2):671-8 - PubMed

Publication types

MeSH terms

LinkOut - more resources