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. 1996 May;52(1):53-7.
doi: 10.1016/0378-8741(96)01391-8.

In vitro cytotoxicity and immunomodulating property of Rhaphidophora korthalsii

K T Wong  1 , B K Tan
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In vitro cytotoxicity and immunomodulating property of Rhaphidophora korthalsii

K T Wong et al. J Ethnopharmacol. 1996 May.

Abstract

An in vitro cytotoxic screening of extracts of Rhaphidophora korthalsii indicated cytotoxicity in the ether fraction. ED50 values of the extract against P388, Molt 4, KB and SW 620 were 12, 14, 8 and 13 micrograms/ml, respectively. The extract was relatively more toxic on P388 and Molt 4 cell lines at concentrations of 50 micrograms/ml and 100 micrograms/ml. Screening with mouse splenocytes showed that the hot water extract had splenocytes stimulating activity.

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