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Clinical Trial
. 1996 May;13(3):186-8.
doi: 10.1136/emj.13.3.186.

Topical analgesia for superficial corneal injuries

A K Brahma  1 , S Shah, V F Hillier, D McLeod, T Sabala, A Brown, J Marsden
Affiliations
Clinical Trial

Topical analgesia for superficial corneal injuries

A K Brahma et al. J Accid Emerg Med. 1996 May.

Abstract

Objective: To assess the analgesic effects of a topical non-steroidal anti-inflammatory agent, flurbiprofen 0.03%, during healing after superficial corneal injuries.

Methods: 401 patients treated for corneal abrasion in a five month period were randomly allocated to one of four treatment groups: polyvinyl alcohol alone (control), homatropine 2%, flurbiprofen 0.03%, or homatropine 2% followed by flurbiprofen 0.03%. Treatments were given for 48 h. Ocular pain was recorded on a visual analogue scale by the patients over the first 24 h, and use of oral analgesics was also recorded. Usable responses were received from 224 patients (55.8%).

Results: Patients treated with flurbiprofen had significantly lower pain scores for the 24 h duration of the study than controls (P < 0.05).

Conclusions: Flurbiprofen eye drops provide more effective pain relief than traditional treatments for superficial corneal injuries.

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