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Case Reports
. 1996 Apr;35(4):310-4.
doi: 10.2169/internalmedicine.35.310.

An unusual case of brucellosis in Japan: difficulties in the differential diagnosis from pulmonary tuberculosis

H Takahashi  1 , S Tanaka, K Yoshida, H Hoshino, H Sasaki, K Takahashi, K Kimura, N Fujii, H Kimura, M Mori, S Abe
Affiliations
Free article
Case Reports

An unusual case of brucellosis in Japan: difficulties in the differential diagnosis from pulmonary tuberculosis

H Takahashi et al. Intern Med. 1996 Apr.
Free article

Abstract

Human brucellosis is an imported zoonosis extremely uncommon in Japan. Brucellosis was found in a 38-year-old surgeon who had never been abroad; he developed intrapulmonary infiltrates and pleural thickening indistinguishable from pulmonary tuberculosis. Despite extensive antibiotic therapy for tuberculosis he developed systemic serositis. A culture of resected lung tissues grew CO2-required coccobacilli. Polymerase chain reaction test using a specific primer pair for Brucella abortus revealed that the isolated pathogen is highly homologous to B. abortus. We emphasize that undetermined cases of human brucellosis may be present in Japan.

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