Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1996;103(3):355-61.
doi: 10.1007/BF01271247.

Lamotrigine in the treatment of nocturnal myoclonus syndrome (NMS): two case reports

J Staedt  1 , G Stoppe, H Riemann, G Hajak, E Rüther, P Riederer
Affiliations
Clinical Trial

Lamotrigine in the treatment of nocturnal myoclonus syndrome (NMS): two case reports

J Staedt et al. J Neural Transm (Vienna). 1996.

Abstract

In previous investigations we found an increase of D2 dopamine receptors in the striatum of patients with nocturnal myoclonus syndrome (NMS) after treatment with dopamimetics. Under the hypothesis, that, according to animal experiments, the glutamatergic system could be involved in this atypical dopaminergic up-regulation in NMS. The glutamate release inhibitor lamotrigine was tested in up to now two NMS patients. The results and the success of this approach and its implications are discussed.

PubMed Disclaimer

References

    1. J Neural Transm Gen Sect. 1995;99(1-3):187-93 - PubMed
    1. J Neural Transm Gen Sect. 1993;91(2-3):255-69 - PubMed
    1. Neuroscience. 1991;41(1):1-24 - PubMed
    1. Trends Neurosci. 1989 Oct;12(10):366-75 - PubMed
    1. Psychiatry Clin Neurosci. 2001 Jun;55(3):305-10 - PubMed

Publication types

LinkOut - more resources