Comparative Study
Comparison of the anti-inflammatory effect and gastrointestinal tolerability of aceclofenac and diclofenac
Affiliations
- PMID: 8740087
Item in Clipboard
Comparative Study
Comparison of the anti-inflammatory effect and gastrointestinal tolerability of aceclofenac and diclofenac
Arzneimittelforschung.
1996 Apr.
Abstract
Aceclofenac (CAS 89796-99-6) and diclofenac (CAS 15307-79-6) are orally effective non-steroidal anti-inflammatory drugs. Their anti-inflammatory and potential gastrointestinal damaging effects were compared following single and repeated administration (5 days). Both drugs exerted an anti-inflammatory activity and showed a similar gastrointestinal tolerability in the rat.
Similar articles
-
Pharmacology of the potent new non-steroidal anti-inflammatory agent aceclofenac.Arzneimittelforschung. 1991 Dec;41(12):1265-76. Arzneimittelforschung. 1991. PMID: 1815528
-
Gastrointestinal safety and anti-inflammatory effects of a hydrogen sulfide-releasing diclofenac derivative in the rat.Gastroenterology. 2007 Jan;132(1):261-71. doi: 10.1053/j.gastro.2006.11.042. Epub 2006 Nov 29. Gastroenterology. 2007. PMID: 17241876
-
Potentiation of diclofenac-induced anti-inflammatory response by aminoguanidine in carrageenan-induced acute inflammation in rats: the role of nitric oxide.Inflamm Res. 2003 Sep;52(9):378-82. doi: 10.1007/s00011-003-1189-1. Inflamm Res. 2003. PMID: 14504665
-
[Pharma-clinics. The drug of the month. Aceclofenac (Biofenac)].Rev Med Liege. 1999 Jan;54(1):62-4. Rev Med Liege. 1999. PMID: 10081315 Review. French.
-
[The use of aceclofenac (airtal) in the outpatient practice of the orthopedic traumatologist].Khirurgiia (Mosk). 2017;(12):103-106. doi: 10.17116/hirurgia201712103-106. Khirurgiia (Mosk). 2017. PMID: 29286041 Review. Russian. No abstract available.
Cited by
-
Aceclofenac: a reappraisal of its use in the management of pain and rheumatic disease.Drugs. 2001;61(9):1351-78. doi: 10.2165/00003495-200161090-00012. Drugs. 2001. PMID: 11511027 Review.
-
Safety and effectiveness of 4-week therapy with aceclofenac controlled release once a day.Sci Rep. 2022 Oct 3;12(1):16519. doi: 10.1038/s41598-022-20633-6. Sci Rep. 2022. PMID: 36192565 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources