Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1996:(219):29-32.

Ocular myopathy and mitochondrial DNA deletion. A presentation of seven identified Danish patients

P J Magalhães  1 , O Sjö, S Nørby
Affiliations
  • PMID: 8741113

Ocular myopathy and mitochondrial DNA deletion. A presentation of seven identified Danish patients

P J Magalhães et al. Acta Ophthalmol Scand Suppl. 1996.

Abstract

This paper summarizes the data on Danish patients with ocular myopathy and mitochondrial DNA deletion (delta mtDNA). To date, a single Danish patient harbouring delta mtDNA has been reported. In the present study we have identified seven additional ones and characterized the nature of their deletion, both qualitatively and quantitatively. All patients are sporadic cases each with a single deletion in the range of 2.3-78 kb, the delta mtDNA accounting for 10-75% of the total mtDNA in the biopsy analyzed. The clinical severity correlates with the percentage of deletion molecules, and not with the size of the deletion.

PubMed Disclaimer

Publication types

Substances