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. 1977 Jul;90(1):125-9.

The lumi-aggregometer: a new instrument for simultaneous measurement of secretion and aggregation by platelets

R D Feinman, J Lubowsky, I Charo, M P Zabinski
  • PMID: 874364

The lumi-aggregometer: a new instrument for simultaneous measurement of secretion and aggregation by platelets

R D Feinman et al. J Lab Clin Med. 1977 Jul.

Abstract

We have developed a new instrument that simultaneously monitors aggregation and secretion of ATP from the same sample of platelets. Aggregation is determined by the usual turbidimetric method; secretion of ATP is followed by measuring luminescence from the firefly luciferase system at right angles to the aggregometer light path. Data are recorded on a two-pen strip chart recorder and reveal the temporal relations between the two platelet responses.

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