[Pulmonary plasmacytoma. Apropos of a case. Review of the literature]

Abstract

A 65 old man had a solitary primary pulmonary plasmacytoma. Serum immunoelectrophoresis revealed an immunoglobulin G Lambda M-protein. Screening for multiple myeloma with bone marrow biopsy and skeletal survey were negative. The patient underwent left lower lobectomy associated with resection of mediastinal lymph nodes. Immunoperoxydase staining of the mass revealed a monoclonal plasma cell population producing IgG, Lambda chains. No adjuvant chemotherapy or radiation therapy was performed. In few weeks, the paraprotein durably disappeared. Four years later, the patient is well and has no evidence of recurrence or myelomatosis. Authors emphasize the rarity of this tumor. The best treatment of pulmonary plasmacytoma is discussed.