How to make my blood boil
- PMID: 8747452
- DOI: 10.1016/s0969-2126(01)00263-5
How to make my blood boil
Abstract
Two recent papers comparing the structure of a hyperthermophilic protein with its mesophilic counterpart both conclude that large networks of ion-pairs are important for hyperthermostability. How and why is not yet clear.
Comment on
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The structure of Pyrococcus furiosus glutamate dehydrogenase reveals a key role for ion-pair networks in maintaining enzyme stability at extreme temperatures.Structure. 1995 Nov 15;3(11):1147-58. doi: 10.1016/s0969-2126(01)00251-9. Structure. 1995. PMID: 8591026
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2.0 A structure of indole-3-glycerol phosphate synthase from the hyperthermophile Sulfolobus solfataricus: possible determinants of protein stability.Structure. 1995 Dec 15;3(12):1295-306. doi: 10.1016/s0969-2126(01)00267-2. Structure. 1995. PMID: 8747456
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