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Review
. 1995 Dec;5(6):825-9.
doi: 10.1016/0959-440x(95)80017-4.

What makes a binding site a binding site?

Affiliations
Review

What makes a binding site a binding site?

D Ringe. Curr Opin Struct Biol. 1995 Dec.

Abstract

Organic probe molecules have recently been used to define hydrophobic binding sites on the surface of proteins. It appears that the presence of water on the surface of a protein plays a crucial role in the interaction between that protein and its binding site.

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