doi: 10.1021/jm00217a015.
Anticoccidial 1-substituted 4(1H)-pyridinone hydrazones
- PMID: 874968
- DOI: 10.1021/jm00217a015
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Anticoccidial 1-substituted 4(1H)-pyridinone hydrazones
J Med Chem.
1977 Jul.
Abstract
4-Chlorobenzaldehyde 1-(4-chlorophenyl)-4(1H)-pyridinylidene hydrazone fluorusulfonate (4) was found to have excellent anticoccidial activity in chickens. The synthesis and biological evaluation of related analogues are presented. Presumably 4 shares a common mechanism of action with robenidine (25) since it was not active on a robenidine tolerant strain of E. tenella. Structural comparisons of the two molecules are presented.
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