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Case Reports
. 1996 Jan;155(1):46-8.
doi: 10.1007/BF02115626.

Hyponatraemia and cerebral convulsion due to short term DDAVP therapy for control of enuresis nocturna

M Schwab  1 , D Wenzel, H Ruder
Affiliations
Case Reports

Hyponatraemia and cerebral convulsion due to short term DDAVP therapy for control of enuresis nocturna

M Schwab et al. Eur J Pediatr. 1996 Jan.

Abstract

Desmopressin (DDAVP) is frequently used in the treatment of primary isolated enuresis nocturna if other approaches have failed. We report a further case of hyponatraemia and cerebral convulsion due to water intoxication after intranasal DDAVP application by a 6 year-old boy with enuresis.

Conclusion: Although adverse reactions in DDAVP (e.g. hyponatraemia) are rare, it should not be considered as the first choice treatment of enuresis nocturna and only be used with caution.

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