Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1996 Sep;59(3):613-9.

A second locus for Rieger syndrome maps to chromosome 13q14

J C Phillips  1 , E A del Bono, J L Haines, A M Pralea, J S Cohen, L J Greff, J L Wiggs
Affiliations

A second locus for Rieger syndrome maps to chromosome 13q14

J C Phillips et al. Am J Hum Genet. 1996 Sep.

Abstract

Rieger syndrome is a genetically and phenotypically heterogeneous disorder typically characterized by malformations of the eyes, teeth, and umbilicus. The syndrome is inherited as an autosomal dominant trait and exhibits significant variable expressivity. One locus associated with this disorder has been mapped to 4q25. Using a large four-generation pedigree, we have identified a second locus for Rieger syndrome located on chromosome 13q14.

PubMed Disclaimer

References

    1. Nature. 1996 Mar 14;380(6570):152-4 - PubMed
    1. Trans Am Ophthalmol Soc. 1983;81:736-84 - PubMed
    1. Genomics. 1994 May 15;21(2):299-303 - PubMed
    1. Proc Natl Acad Sci U S A. 1992 Sep 15;89(18):8754-8 - PubMed
    1. Hum Mol Genet. 1995 Aug;4(8):1435-9 - PubMed

Publication types