[Immunological indicators in patients with pulmonary tuberculosis in the presence of drug-resistant Mycobacteria]
- PMID: 8754879
[Immunological indicators in patients with pulmonary tuberculosis in the presence of drug-resistant Mycobacteria]
Abstract
Immunological indices for 121 pulmonary tuberculosis (PT) patients discharging drug-resistant M. tuberculosis were compared to those for 87 PT patients with M. tuberculosis sensitive to antibacterial drugs. The patients with drug-resistant bacteria before hospitalization had lower count of T-lymphocytes, altered proportion T-helpers/T-suppressors, reduced ability of T-lymphocytes for blast transformation in the presence of PHA and PPD. T-lymphocyte functional activity remained inhibited as compared to those patients discharging drug-sensitive mycobacteria.
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