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. 1977 Jul-Aug;6(4):287-91.
doi: 10.1016/0047-6374(77)90030-6.

Developmental patterns of plasma TSH, T4 and T3 in rats deprived of light from birth

S Ooka-Souda, D J Draves, P S Timiras

Developmental patterns of plasma TSH, T4 and T3 in rats deprived of light from birth

S Ooka-Souda et al. Mech Ageing Dev. 1977 Jul-Aug.

Abstract

Plasma levels of TSH, T4 and T3 in the rat show characteristic developmental patterns within the first postnatal month, with TSH reaching a peak on day 13, T4 on day 16 and T3 on day 20. In dark-reared rats, a significant reduction in plasma T3 associated with low plasma T4 as well as high plasma TSH suggest that light-deprivation from birth impairs and/or delays maturation of pituitary-thyroid axis.

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