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. 1996 Jul;21(7):237-41.

CPx-type ATPases: a class of P-type ATPases that pump heavy metals

M Solioz  1 , C Vulpe
Affiliations
  • PMID: 8755241

CPx-type ATPases: a class of P-type ATPases that pump heavy metals

M Solioz et al. Trends Biochem Sci. 1996 Jul.

Abstract

ATP-driven heavy metal pumps represent a newly defined class of proteins that translocate toxic and essential metals across biological membranes. These transporters form a separate evolutionary branch of the ion-transporting P-type ATPases. We propose to call these enzymes CPx-type ATPases, based on the common novel feature of a conserved intramembranous cysteine-proline-cysteine or cysteine-proline-histidine motif.

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  • P-type ATPases.
    Lutsenko S, Kaplan JH. Lutsenko S, et al. Trends Biochem Sci. 1996 Dec;21(12):467. doi: 10.1016/s0968-0004(96)20029-5. Trends Biochem Sci. 1996. PMID: 9009828 No abstract available.

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