Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1996 Aug;178(15):4429-37.
doi: 10.1128/jb.178.15.4429-4437.1996.

The integrons In0, In2, and In5 are defective transposon derivatives

H J Brown  1 , H W Stokes, R M Hall
Affiliations

The integrons In0, In2, and In5 are defective transposon derivatives

H J Brown et al. J Bacteriol. 1996 Aug.

Abstract

The class 1 integrons In0, In2, and In5, found in different locations in pVS1, Tn21, and pSCH884, have closely related structures. All three integrons contain an insertion sequence, IS1326, that is a new member of the IS21 family. IS1326 has caused deletions of adjacent 3'-conserved segment and transposition module sequences, and all three integrons retain a complete copy of only one of four genes required for transposition of related transposons and are thus defective transposon derivatives. In2 contains an additional insertion sequence, IS1353, located within IS1326. IS1353 is a member of the IS3 family and appears to have been acquired after the integron was inserted into an ancestral mercury resistance transposon to create the ancestor of Tn21 and several other transposons that are close relatives of Tn21.

PubMed Disclaimer

References

    1. J Bacteriol. 1990 Dec;172(12):6689-96 - PubMed
    1. EMBO J. 1990 Dec;9(12):4055-63 - PubMed
    1. Plasmid. 1990 Nov;24(3):163-89 - PubMed
    1. Nucleic Acids Res. 1991 Jul 25;19(14):3907-11 - PubMed
    1. Nucleic Acids Res. 1991 Aug 25;19(16):4377-85 - PubMed

Publication types