Interleukin-8 gene expression in Staphylococcus aureus-infected endothelial cells
- PMID: 8757884
- PMCID: PMC174238
- DOI: 10.1128/iai.64.8.3407-3409.1996
Interleukin-8 gene expression in Staphylococcus aureus-infected endothelial cells
Abstract
Interleukin-8 (IL-8) plays a crucial role in the migration of neutrophils to bacterium-infected sites. This study investigated IL-8 induction in Staphylococcus aureus-infected endothelial cells (EC). We observed that S. aureus-infected EC were induced to express both IL-8 mRNA and protein, which can promote transmigration of neutrophils across an EC monolayer.
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