Antibacterial neoclerodane diterpenoids from Ajuga lupulina
- PMID: 8759163
- DOI: 10.1021/np960385s
Antibacterial neoclerodane diterpenoids from Ajuga lupulina
Abstract
The whole plants of Ajuga lupulina afforded five compounds, including three new clerodane diterpenes, lupulins A-C (1-3), whose structures were elucidated by spectral methods. Among these compounds, lupulins A (1) and B (2) as well as the acid hydrolysate (5) of lupulin D (4) showed antibacterial activities against Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli.
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