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Comparative Study
. 1996 Jun;114(2):217-23.
doi: 10.1016/0305-0491(95)02135-3.

Distribution of phosphoglycerate mutase isozymes in rat, rabbit and human tissues

N Durany  1 , J Carreras
Affiliations
Comparative Study

Distribution of phosphoglycerate mutase isozymes in rat, rabbit and human tissues

N Durany et al. Comp Biochem Physiol B Biochem Mol Biol. 1996 Jun.

Abstract

The distribution of phosphoglycerate mutase isozymes (types MM, MB and BB) in rat, rabbit and human tissues has been studied by electrophoresis on cellulose acetate and by highly-resolutive ion exchange chromatography. In the three species, muscle is the tissue with higher phosphoglycerate mutase activity. Heart is the only tissue with the three phosphoglycerate mutase isozymes in substantial amounts. Skeletal muscle contains mostly type MM isozyme and the other tissues possess almost exclusively type BB isozyme. Even in the presence of inhibitors, adenylate kinase can interfere with the staining reactions when large samples are analyzed and a long period of incubation is required.

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