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. 1996 Apr 15;130(8):511-4, 584.

[Ifosfamide in pediatric malignancy--experiences in the Northern Israel Oncology Center]

[Article in Hebrew]
A Roguin  1 , M W Ben Arush, A Higasi, A Kuten
Affiliations
  • PMID: 8765870

[Ifosfamide in pediatric malignancy--experiences in the Northern Israel Oncology Center]

[Article in Hebrew]
A Roguin et al. Harefuah. .

Abstract

The records of 46 children treated with ifosfamide between 1987-1994 were analyzed. 24 received the drug as first-line chemotherapy in combination with vincristine and etoposide or with adriamycin, vincristine and cyclophosphamide. Complete remission was achieved in 8/10 children with soft tissue sarcoma, 7/8 with Ewing's sarcoma, 2/2 with ovarian carcinoma and 2/2 with clear cell sarcoma of the kidney. 22 children in whom first-line chemotherapy failed were then treated with ifosfamide and etoposide. Complete remission was achieved in 7/10 children with osteosarcoma, 1/2 with Wilms' tumor and 1/3 with neuroblastoma.

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