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. 1976 Jun;3(6):1549-59.
doi: 10.1093/nar/3.6.1549.

Protonated polynucleotide structures, 20. Interaction between poly(dG)-poly(dC) and poly(rC).1

Free PMC article

Protonated polynucleotide structures, 20. Interaction between poly(dG)-poly(dC) and poly(rC).1

B L Haas et al. Nucleic Acids Res. 1976 Jun.
Free PMC article

Abstract

A study of the interaction between poly(dG)-poly(dC) and poly(rC) demonstrates that, at neutral pH and high ionic strength, there is replacement of the dC strand by poly(rC). At acid pH, formation of a triple-stranded complex which equally may involve the replacement phenomenon is observed. There is no evidence for interaction at neutral pH between poly(dG)-poly(dC) and oligo(rC), while a three-stranded complex is formed at acid pH. These data are consistent with the studies of comparative stabilities of double stranded deoxy or ribo polymers and deoxy-ribo hybrids.

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References

    1. Eur J Biochem. 1975 Feb 21;51(2):369-76 - PubMed
    1. Nucleic Acids Res. 1976 Jan;3(1):205-18 - PubMed
    1. J Mol Biol. 1964 Sep;9:624-37 - PubMed
    1. Nucleic Acids Res. 1975 Mar;2(3):353-60 - PubMed
    1. Can J Biochem. 1973 Apr;51(4):436-49 - PubMed