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. 1996 Apr;4(1):77-86.

Characterization and interpretation of electrical signals from random networks of cultured neurons

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  • PMID: 8773310

Characterization and interpretation of electrical signals from random networks of cultured neurons

M Bove et al. Technol Health Care. 1996 Apr.

Abstract

The main purpose of this paper is to describe several software tools specifically adapted to characterize the electrophysiological behavior of a population of neurons coupled to a planar array of microtransducers by analyzing the recorded signals. Both graphic and signal processing tools are considered. They include: image analysis of the neuronal network topology, peak detection procedure, multi-graphics visualization, spike classification, cross-correlation, interspike and interbursting interval analysis. These tools are utilized to characterize changes induced in the electrophysiological behavior of populations of cultured neurons by modifications to the medium-culture.

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